A new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments. The researchers successfully used the new ‘Cas9 mouse’ model to edit multiple genes in a variety of cell types, and to model lung adenocarcinoma, one of the most lethal human cancers.
http://feeds.sciencedaily.com/~r/sciencedaily/~3/Xm7m05diDvU/140925132835.htm
Researchers engineer ‘Cas9’ animal models to study disease, inform drug discovery
25 September 2014
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