Lack of dopamine transmission through D1 receptors disturbs information flow through the ‘direct pathway’ in the basal ganglia, and ends up in difficulty in initiating voluntary movements, researchers have discovered.
http://www.sciencedaily.com/releases/2015/10/151006083855.htm
Lack of D1 receptor leads to slowness of movements in Parkinson’s disease
6 October 2015
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